IBJ Clinical Pharmacology: Articles



IBJ Clinical Pharmacology publishes original articles, reviews, case reports, etc., in the area of Clinical Pharmacology, including pharmacokinetics, pharmacodynamics, pharmacometrics, therapeutic drug monitoring, toxicology, pharmacogenetics, drug, cell and gene therapy, pharmacoepidemiology, study of drug use, pharmacoeconomics, drug regulation. Especially interested in cross-sectional studies and in national and international collaborative efforts.

Case report

La importancia de la información de seguridad en las fichas técnicas: a propósito de un caso.

Year: 2017 Volume: 1 Issue: 1 Number: e0010

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The information about the safety of a drug is included in the Summary of Product Characteristics (SmPC), in section “Undesirable effects” and it has got a great importance for healthcare professionals.


Publication date:

Language: Spanish

Keywords: DRESS, pseudolinfoma, fenitoína, reacción adversa a medicamento, RAM, ficha técnica.

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Protocol

Pharmacokinetic characterization of the population with hemophilia A in Spain, using an online medical application based on a published population model and a Bayesian algorithm.

Year: 2017 Volume: 1 Issue: 1 Number: e0009

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The main objective of this prospective observational study is to describe the pharmacokinetic profile of patients with hemophilia A in prophylaxis with Advate® in Spain using myPKFiT®.


Publication date:

Language: English

Keywords: Pharmacokinetic, hemophilia, online medical application, Bayesian algorithm.

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Protocol

Phase IIIb, open label randomised clinical trial to compare pain relief between methoxyflurane and standard of care for treating patients with trauma pain in Spanish Emergency Units (InMEDIATE): Study protocol.

Year: 2017 Volume: 1 Issue: 1 Number: e0008

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Despite advances in treatments for acute pain with new medications and development of widely accepted guidelines, inadequate assessment and management of acute pain still remain major problems in prehospital settings and emergency departments.


Publication date:

Language: English

Keywords: Methoxyflurane, Inhaled anesthetic, Inhaled analgesic, Sedation, Traumatic pain, Emergency units.

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Protocol

Acute and chronic paracetamol overdose in paediatric population: Protocol of a prospective study of cohort to evaluate clinic factor and biomarkers to predict development of hepatotoxicity.

Year: 2017 Volume: 1 Issue: 1 Number: e0007

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In Spain, 30% of cases of acute liver failure remaining undetermined. Paracetamol is the main drug causing acute liver failure in children of some countries like the United States, UK and other European countries.


Publication date:

Language: English

Keywords: Paracetamol, overdose, toxicity, hepatotoxicity, acute liver failure, paediatric population, biomarkers, pharmacokinetics, pharmacogenetics, metabolomics.

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Case report

Síndrome nefrótico secundario a glomerulonefritis membranosa asociada al tratamiento con litio.

Year: 2017 Volume: 1 Issue: 1 Number: e0006

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El litio es un metal alcalino que constituye un tratamiento ampliamente establecido en el trastorno afectivo bipolar desde hace décadas...


Publication date:

Language: Spanish

Keywords: Case report, Carbonato de litio, Glomerulonefritis membranosa, Síndrome nefrótico, Proteinuria.

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Protocol

Effect of the CYP3A5, CYP3A4, CYP3A7, ABCB1, POR and NR1I2 genes in the pharmacokinetics of tacrolimus in a pediatric cohort with stable serum concentrations after renal transplantation: study protocol.

Year: 2017 Volume: 1 Issue: 1 Number: e0005

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Therapeutic response to pharmacological therapy in humans shows large intrapatient and interpatient variability both in treatment efficacy and adverse drug reactions (ADR).


Publication date:

Language: English

Keywords: Tacrolimus, transplantation, pharmacokinetics, pharmacogenetics, cytochrome P450, metabolism.

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Original

Infections as cause of urgent hospital admission in adults in a tertiary hospital

Year: 2017 Volume: 1 Issue: 1 Number: e0004

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To study the prevalence of bacterial infections as a cause of hospital admission through the Emergency Room (ER), identifying the causal agent...


Publication date:

Language: Spanish

Keywords: Bacterial infection, Emergency Department, Hospital admission, Antibiotics therapy, Patient’s outcome

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Case report

Acute Pancreatitis by liposomal amphotericin B

Year: 2016 Volume: 1 Issue: 1 Number: e0003

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Acute pancreatitis is not listed in the Summary of Product Characteristics of LAB, although some non-severe cases of pancreatitis toxicity after LAB are...


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Language: English

Keywords: case-report, liposomal amphotericin B, pancreatitis, Adverse-drug reaction, leishmaniasis.

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Perspective

Uso de la farmacogenética en la práctica clínica

Year: 2016 Volume: 1 Issue: 1 Number: e0002

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Los importantes avances realizados en los últimos años en el campo de la genética y la genómica han abierto la puerta a conocimientos y técnicas con un gran potencial de mejorar el...


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Language: Spanish

Keywords: farmacogenética, implementación, genotipado anticipado.

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Those authors with not funded articles who have their articles approved for publication will be granted a publication fee exemption.

(The fee waiver does not include the layout editing service).