IBJ Clinical Pharmacology: Articles



IBJ Clinical Pharmacology publishes original articles, reviews, case reports, etc., in the area of Clinical Pharmacology, including pharmacokinetics, pharmacodynamics, pharmacometrics, therapeutic drug monitoring, toxicology, pharmacogenetics, drug, cell and gene therapy, pharmacoepidemiology, study of drug use, pharmacoeconomics, drug regulation. Especially interested in cross-sectional studies and in national and international collaborative efforts.



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IBJ CP: Special Issue # 3, V Jornadas PIELenRED. (12 Abstracts)



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IBJ CP: Special Issue # 2, III Jornadas Científicas SEFC. (10 Abstracts)



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IBJ CP: Special Issue # 1, IV Jornada de PielenRed. (9 Abstracts)



Protocol

GKounis syndrome secondary to heparin in a newborn with hypoplastic left heart.

Year: 2020 Volume: 1 Issue: 1 Number: e0015

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Kounis syndrome (KS) is an acute coronary syndrome (ACS) described in relationship with drugs or stents. KS was suspected in a full-term newborn who underwent a Rashkind-atrioseptostomy and stenting that periodically developed episodes of ACS.


Publication date:

Language: English

Keywords: Kounis syndrome, newborn, adverse drug reaction, coronary artery spasm.

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Protocol

Gentamicin serum concentrations after reinfusion of blood in patients undergoing arthroplasty with gentamicin-loaded bone cement.

Year: 2020 Volume: 1 Issue: 1 Number: e0014

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Cement is sometimes applied to fix prostheses during arthroplasty. The cement can contain antibiotics for prophylaxis or treatment of joint infection. Gentamicin in cement is released gradually into its surroundings and can reach toxic concentrations in recovered blood.


Publication date:

Language: English

Keywords: Gentamicin, arthroplasty, bone cements, blood, reinfusion.

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Protocol

Utility of a computer tool for detection of potentially inappropriate medications in older patients in a tertiary hospital.

Year: 2020 Volume: 1 Issue: 1 Number: e0013

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As we believe it is an important problem in our environment, we determined the prevalence of potentially inappropriate medications (PIM) using the STOPP/START, Beers and PRISCUS criteria, and also determined the clinical variables related to the prescription of PIMs in older adults.


Publication date:

Language: English

Keywords: CheckTheMeds®, Potentially Inappropriate Prescribing, STOPP – START, Beers, PRISCUS.

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Protocol

A randomized clinical trial to evaluate two guidelines for the administration of ibuprofen in the treatment of echo-guided persistent ductus arteriosus.

Year: 2019 Volume: 1 Issue: 1 Number: e0012

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Patent ductus arteriosus (PDA) is a common condition of preterm infants and it is associated to significant morbidity and mortality. The best therapeutic option for PDA closure remains controversial.


Publication date:

Language: Spanish

Keywords: Ductus arteriosus, ibuprofen, necrotizing enterocolitis, echocardiography.

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Case report

DRESS en paciente con toxoplasmosis y síndrome antisintetasa.

Year: 2018 Volume: 1 Issue: 1 Number: e0011

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Se define como síndrome de DRESS a una reacción cutánea grave caracterizada por la aparición de erupción cutánea, adenopatías, fiebre, eosinofilia, leucocitosis y/o afectación orgánica a las...


Publication date:

Language: Spanish

Keywords: DRESS, TTL, SULFAMIDAS, TRIMETOPRIM, PIRIMETAMINA.

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Case report

La importancia de la información de seguridad en las fichas técnicas: a propósito de un caso.

Year: 2017 Volume: 1 Issue: 1 Number: e0010

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The information about the safety of a drug is included in the Summary of Product Characteristics (SmPC), in section “Undesirable effects” and it has got a great importance for healthcare professionals.


Publication date:

Language: Spanish

Keywords: DRESS, pseudolinfoma, fenitoína, reacción adversa a medicamento, RAM, ficha técnica.

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Protocol

Pharmacokinetic characterization of the population with hemophilia A in Spain, using an online medical application based on a published population model and a Bayesian algorithm.

Year: 2017 Volume: 1 Issue: 1 Number: e0009

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The main objective of this prospective observational study is to describe the pharmacokinetic profile of patients with hemophilia A in prophylaxis with Advate® in Spain using myPKFiT®.


Publication date:

Language: English

Keywords: Pharmacokinetic, hemophilia, online medical application, Bayesian algorithm.

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Protocol

Phase IIIb, open label randomised clinical trial to compare pain relief between methoxyflurane and standard of care for treating patients with trauma pain in Spanish Emergency Units (InMEDIATE): Study protocol.

Year: 2017 Volume: 1 Issue: 1 Number: e0008

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Despite advances in treatments for acute pain with new medications and development of widely accepted guidelines, inadequate assessment and management of acute pain still remain major problems in prehospital settings and emergency departments.


Publication date:

Language: English

Keywords: Methoxyflurane, Inhaled anesthetic, Inhaled analgesic, Sedation, Traumatic pain, Emergency units.

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Protocol

Acute and chronic paracetamol overdose in paediatric population: Protocol of a prospective study of cohort to evaluate clinic factor and biomarkers to predict development of hepatotoxicity.

Year: 2017 Volume: 1 Issue: 1 Number: e0007

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In Spain, 30% of cases of acute liver failure remaining undetermined. Paracetamol is the main drug causing acute liver failure in children of some countries like the United States, UK and other European countries.


Publication date:

Language: English

Keywords: Paracetamol, overdose, toxicity, hepatotoxicity, acute liver failure, paediatric population, biomarkers, pharmacokinetics, pharmacogenetics, metabolomics.

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