IBJ Clinical Pharmacology

IBJ Clinical Pharmacology publishes original articles, reviews, case reports, etc., in the area of Clinical Pharmacology, including pharmacokinetics, pharmacodynamics, pharmacometrics, therapeutic drug monitoring, toxicology, pharmacogenetics, drug, cell and gene therapy, pharmacoepidemiology, study of drug use, pharmacoeconomics, drug regulation. Especially interested in cross-sectional studies and in national and international collaborative efforts.

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Protocolo: Effect of the CYP3A5, CYP3A4, CYP3A7, ABCB1, POR and NR1I2 genes in the pharmacokinetics of tacrolimus in a pediatric cohort with stable serum concentrations after renal transplantation: study protocol.

Protocolo: Effect of the CYP3A5, CYP3A4, CYP3A7, ABCB1, POR and NR1I2 genes in the pharmacokinetics of tacrolimus in a pediatric cohort with stable serum concentrations after renal transplantation: study protocol.

Año: 2017 Volumen: 1 Edición: 1 Número: e0005

Palabras clave : Tacrolimus, transplantation, pharmacokinetics, pharmacogenetics, cytochrome P450, metabolism.

Therapeutic response to pharmacological therapy in humans shows large intrapatient and interpatient variability both in treatment efficacy and adverse drug reactions (ADR).

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